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目的：探讨丙肝抗体联合丙肝核心抗原检测在丙型肝炎早期诊断中的意义。方法：选取2013年1月到2014年12月在我院进行体检的人群23771例，所有体检者都进行了丙肝抗体检测，而21928例体检者进行了丙肝核心抗原检测，检测方法都为ELISA法。结果：ELISA法对于丙肝抗体与丙肝核心抗原的检测阳性率分别为0.70%和0.10%。结论：丙肝抗体联合丙肝核心抗原检测在丙型肝炎早期诊断中的应用能有效判定丙型肝炎的传染性，值得推广应用。“,”Objective To discuss the significance of hepatitis C antibody combined hepatitis C virus core antigen test in the early diagnosis of hepatitis C.Methods We selected 23771 cases of physical examination from January 2013 to December 2014 in our hospital, all subjects were detected for hepatitis C antibody, 21928 subjects were tested for hepatitis C core antigen, detection method is ELISA. Results ELISA method was used to detect the positive rate for hepatitis C antibody and hepatitis C core antigen were 0.70% and 0.10%. Conclusion Hepatitis C antibody combined hepatitis C virus core antigen test can determine effectively hepatitis C infectivity in the early diagnosis of hepatitis C, it is worthy of popularization and application.