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自1955年 Zollingen 和 Ellison 报告胰岛肿瘤和消化性溃疡的联系以来,关于胃胰关系的研究有了很大的进展,现已明确不仅外分泌,在内分泌方面也存在着复杂的调节机能。胃泌素、促胰液素酶、缩胆囊素等体液因素和神经因素都起着重要的作用。下面重点叙述胃胰的外分泌调节。胃对胰外分泌的影响1.胃酸的作用1902年 Bayliss 和 Starling 向被阻断神经的十二指肠内注入盐酸时,发现胰液分泌。从而得出了十二指肠内酸性化使胰液分泌的结论。并认为是通过促胰液素酶产生的。Meyer 等对
Since Zollingen and Ellison reported the association between islet tumor and peptic ulcer in 1955, great progress has been made in the study of the relationship between the stomach and the pancreas. It is now clear that not only the exocrine but also the complex regulatory function in endocrine. Gastrin, secretinase, cholecystokinin and other humoral and neurological factors play an important role. The following focuses on the exocrine regulation of stomach and pancreas. Effect of stomach on pancreatic exocrine 1. Effect of gastric acid In 1902, when Bayliss and Starling injected hydrochloric acid into the blocked duodenum, pancreatic juice was found to be secreted. Thus draw the duodenal acidification of pancreatic juice secretion conclusion. And is believed to be produced by secretinase. Meyer and so on