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目的 探讨精神障碍伴发阻塞性睡眠呼吸暂停综合征 (OSAS)患者的临床特点及睡眠生理改变。方法 对 42 0例精神障碍患者进行多导睡眠图 (PSG)检测。将检出的 18例 OSAS与 18例正常对照进行比较。 结果 1病例组打鼾、睡眠憋醒、白天嗜睡、记忆减退症状较对照组明显增多 (P <0 .0 1)。 2与对照组比较 ,病例组醒觉次数、觉醒时间、 期睡眠、鼾声指数及呼吸紊乱指数增高 , 、 期深睡眠减少 ,夜间最低血氧饱和度及韦氏记忆量表分减少 ,最长呼吸及平均呼吸暂停时间延长 (P均 <0 .0 1)。结论 夜间睡眠结构紊乱、低氧血症可能是 OSAS伴发精神障碍的病理基础。
Objective To investigate the clinical features and physiological changes of sleep in patients with mental disorders associated with obstructive sleep apnea syndrome (OSAS). Methods Forty-two patients with mental disorders underwent polysomnography (PSG). 18 cases of OSAS detected and 18 cases of normal control were compared. Results 1 case group snoring, sleep arousal, daytime drowsiness, memory loss symptoms were significantly increased compared with the control group (P <0. 2 Compared with the control group, the number of wakefulness, wakefulness, sleep, snoring index and respiratory disturbance index increased in case group, decreased deep sleep, nighttime lowest oxygen saturation and Wechsler memory scale decreased, the longest breathing And prolonged average apnea duration (all P <0.01). Conclusions Nocturnal sleep disorders and hypoxemia may be the pathological basis of OSAS associated with mental disorders.