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目的观察并总结系统性红斑狼疮并发急腹症的临床诊治方法。方法选择南乐县人民医院40例系统性红斑狼疮并发急腹症患者的临床资料,观察全部患者的临床症状表现,实验室检查、观察患者的活动性与急腹症的关系,给予对症治疗。结果 31例患者发生急腹症与红斑狼疮活动有关,9例与其他因素有关,两组患者红斑狼疮活动度平均分比较,具有明显差异(P<0.05)。实验室检查发现,全部患者均补体C3降低;19例患者给予病理检查发现有增生、炎症改变。31例因红斑狼疮引发急腹症的患者经治疗1~12d后临床症状得到好转,9例因其他原因引发急腹症的患者中,1例因急性胰腺炎导致病情加重外,其他患者均获得好转。腹部CT检查阳性率为58.1%。结论系统性红斑狼疮合并急腹症患者应给予及时的CT及B超等检查,并给予红斑狼疮活动度检查,确认患者发生急腹症的原因后给予对症处理,以降低死亡率,改善预后。
Objective To observe and summarize the clinical diagnosis and treatment of systemic lupus erythematosus complicated by acute abdomen. Methods The clinical data of 40 patients with systemic lupus erythematosus complicated with acute abdomen were selected in Nanle County People’s Hospital. Clinical symptoms and laboratory tests were performed in all patients. The relationship between the activity and acute abdomen was observed and symptomatic treatment was given. Results There were 31 cases of acute abdomen disease and lupus erythematosus activity, 9 cases were related to other factors. There was significant difference (P <0.05) between the two groups in the average activity of lupus erythematosus. Laboratory tests found that all patients were reduced complement C3; 19 patients were given pathological examination found that hyperplasia, inflammation change. The clinical symptoms of 31 patients with acute abdomen caused by lupus were improved after 1 to 12 days of treatment. Among the 9 patients with acute abdomen caused by other reasons, 1 patient was exacerbated by acute pancreatitis and other patients were obtained Better. The positive rate of abdominal CT examination was 58.1%. Conclusions Patients with systemic lupus erythematosus complicated by acute abdomen should be given timely CT and B ultrasound examinations, and the activity of lupus erythematosus should be checked to confirm the cause of acute abdomen patients after symptomatic treatment to reduce the mortality and improve the prognosis.