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矽肺是我国危害工人健康最严重的一种职业病。50年代我国就开始进行中药治疗矽肺的研究,取得一定进展。1960年国内首次合成克矽平[1],70年代开始筛选抗纤维化药物,已从数千个药物中筛选出汉防己甲素、磷酸喹哌、羟基磷酸喹哌、柠檬酸铝等,并于70年代末80年代初用于临床,取
Silicosis is one of the most serious occupational diseases endangering the health of workers in our country. In the 1950s, China began to study the treatment of silicosis with traditional Chinese medicine and made some progress. In 1960, KPS was first synthesized in China [1]. In the 1970s, antifibrotic drugs were screened. Several thousand drugs were used to screen out tetrandrine, quipiper phosphate, quiphyloxiphosphate and aluminum citrate, etc. In the late 70s early 80s for clinical use