男,58岁,杂志编辑。1986年1月23日因高热、寒战7天,昏迷2天,外院诊为伤寒介绍入院。患者1月16日突然出现畏寒,继而寒战,随即发热、头痛。发热39℃,伴恶心,呕吐未消化食物。双下肢酸痛。无腹泻。发热持续不退,日渐上升,第4天到某医院急诊留观1天,经静脉输入葡萄糖,肌注柴胡注射液,口服红霉素、TMP、消炎痛和维生素B_1、C,体温稍下降,后又上升达40℃,头痛不止,胃口欠佳。入院前2天嗜睡,呼之即醒,随之入睡,时有问 Male, 58 years old, magazine editor. January 23, 1986 due to fever, chills 7 days, coma for 2 days, outside the hospital for the introduction of typhoid fever admitted. Patients on January 16 suddenly chills, then chills, then fever, headache. Fever 39 ℃, with nausea, vomiting, undigested food. Lower extremity sore. No diarrhea. Fever continued to rise, rising, the first 4 days to a hospital emergency 1 day observation, intravenous glucose, intramuscular injection of Bupleurum injection, oral erythromycin, TMP, indomethacin and vitamin B_1, C, body temperature decreased slightly , Then up to 40 ℃, headache, poor appetite. Drowsiness 2 days before admission, call wake up, then fall asleep, when asked