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目的:探讨沙眼衣原体(CT)、解脲支原体(Uu)和人型支原体(Mh)感染所致的非淋菌性宫颈炎与早产发生的关系及其对围生儿的影响。方法:采用荧光定量PCR技术对85例早产孕妇(病例组)及85例足月入院正常待产孕妇(对照组)的宫颈分泌物行CT、UU和Mh检测,同时对阳性孕妇的配偶也进行检测,并观察围生儿的情况,并对结果进行分析。结果:病例组孕妇UU、CT、Mh、复合感染率均高于对照组,除Mh+组外差异均具有显著性意义;非淋菌性宫颈炎组低体重儿、新生儿黄疸、肺炎、结膜炎发生率高于阴性组,差异有显著性意义。结论:CT和支原体复合感染所致的非淋菌性宫颈炎可引起并增加早产的发生,同时使围生儿病率升高。
Objective: To investigate the relationship between non-gonococcal cervicitis caused by CT, Uu and Mh and the incidence of prematurity and its effect on perinatal children. Methods: The cervical secretions of 85 premature pregnant women (case group) and 85 full term pregnant women (control group) were detected by fluorescence quantitative PCR for CT, UU and Mh, and the spouses of positive pregnant women were also detected , And observe the situation of perinatal children, and analyze the results. Results: The infection rates of UU, CT and Mh in pregnant women in the case group were higher than those in the control group, except for the Mh + group. There was significant difference in the incidence of UU, CT, Mh and neonates with jaundice, pneumonia and conjunctivitis Rate higher than the negative group, the difference was significant. Conclusion: Nongonococcal cervicitis caused by combined infection of CT and mycoplasma can cause and increase the incidence of prematurity, and meanwhile increase the incidence of perinatal infection.