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Nonalcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease and comprises a wide range of clinical symptoms from nonalcoholic fatty liver to nonalcoholic steatohepatitis (NASH), advanced fibrosis, and cirrhosis (1). Obesity is the major risk factor of NAFLD and its main treatment is lifestyle modifications, including weight management, dietary changes and physical activity (2).