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作者分析庆応大学耳鼻喉科从1957～1975年所见的23例多发性原发恶性肿瘤。在日本文献中,已有这种病人203例报告。在同期内,共经治1093例头颈部恶性瘤,23例(2.1％)的原发恶性瘤为多发性。本组病人的平均年龄为61岁,文献中所报告的病人为60岁,以男性病人居多数。第一及第二肿瘤出现的间隔期,本组9例(39％)同时出现,14例(61％)非同时出现;文献所报告的64例(35.2％)为同时出现,118例(64.8％)为非同时出现。在本组23例中,以上颌窦恶性瘤
The authors analyzed 23 cases of multiple primary malignancies seen at the Department of Otolaryngology at Qing Yu University from 1957 to 1975. In the Japanese literature, 203 cases of such patients have been reported. In the same period, a total of 1093 cases of malignant tumors of the head and neck, 23 cases (2.1%) of primary malignant tumors were multiple. The average age of the patients in this group was 61 years old. The patients reported in the literature were 60 years old, and the majority were male patients. The first and second tumors appeared in the interval, 9 cases (39%) in this group appeared simultaneously, 14 cases (61%) did not occur simultaneously; 64 cases (35.2%) reported in the literature appeared at the same time, 118 cases (64.8 %) is non-simultaneous. In this group of 23 cases, the upper sinus malignant tumor