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目的探讨慢性宫颈炎射频消融术后应用人干扰素α-2b凝胶临床有效性。方法 2009年4月～2010年12月在我院门诊治疗的280例慢性宫颈炎患者,分为两组,研究组141例射频消融术后应用人干扰素α-2b凝胶治疗;对照组139例行单纯射频消融治疗,观察两组病人阴道排液时间、创面感染及脱痂出血发生率,2个月后对比疗效。结果研究组与对照组的阴道排液时间分别为(6.50±0.50)d、(12.2±5.10)d,前者明显少于后者(P<0.01)。创面感染及脱痂出血率研究组明显低于对照组(P<0.05)。研究组与对照组治疗总有效率分别为97.1%和85%,研究组明显高于对照组(P<0.05)。结论慢性宫颈炎射频消融术后应用人干扰素α-2b凝胶可明显减轻副作用并提高临床治愈率,值得临床应用。
Objective To investigate the clinical efficacy of human interferon α-2b gel after radiofrequency ablation of chronic cervicitis. Methods From April 2009 to December 2010, 280 patients with chronic cervicitis treated in our hospital were divided into two groups. The study group consisted of 141 patients treated with IFN-α-2b gel after radiofrequency catheter ablation and the control group 139 Routine simple radiofrequency ablation treatment, the two groups of patients were observed vaginal discharge time, wound infection and the incidence of bleeding scab off, 2 months after the comparison of efficacy. Results The vaginal discharge time of the study group and the control group were (6.50 ± 0.50) d and (12.2 ± 5.10) d, respectively. The former was significantly less than the latter (P <0.01). The wound infection rate and scab bleeding rate in the study group were significantly lower than those in the control group (P <0.05). The total effective rate of the study group and the control group was 97.1% and 85% respectively, which was significantly higher in the study group than in the control group (P <0.05). Conclusion The application of human interferon α-2b gel after radiofrequency ablation of chronic cervicitis can significantly reduce the side effects and improve the clinical cure rate, which deserves clinical application.