内脏器官恶性病变时会出现各种各样的皮肤症状。无论是特异的还是非特异的,均有其重要性。因此我们可根据皮肤表现为线索推断或寻找未知的内脏恶性肿瘤存在,加深对内脏恶性肿瘤的了解,有助于澄清很多困难的诊断。“皮肤—肿瘤综合征”说明了皮肤与内脏恶性肿瘤的密切联系,这种联系可简略地归纳为:①癌前病变中的皮肤症状;②内脏恶性肿瘤引起的皮肤反应;③皮肤肿瘤伴内脏病变。本文拟就前二者关系作如下概述。一、内脏恶性肿瘤的主要皮肤症状:1.恶性黑棘皮病:是内脏恶性肿瘤引起的典型皮肤表现。其临床表现为:乳头状增生、色素沉着角质增生,好发于颈项、腋窝、阴部、股部、也可发生于乳房、关节窝、手背、手掌、足背、足底以及口腔、舌、结膜等粘 A variety of cutaneous symptoms occur when malignant organs of internal organs are involved. It is important whether it is specific or non-specific. Therefore, we can infer or look for the presence of unknown visceral malignancies based on clues to the skin, deepen understanding of visceral malignancies, and help clarify many difficult diagnoses. “Skin-Tumor Syndrome” illustrates the close relationship between skin and visceral malignancy. This link can be briefly summarized as: 1 Skin symptoms in precancerous lesions; 2 Skin reactions caused by visceral malignancies; 3 Skin tumors with internal organs Lesions. This article will outline the following two relationships as follows. First, the main cutaneous symptoms of visceral malignancy: 1. Malignant acanthosis: a typical skin manifestation caused by visceral malignancy. Its clinical manifestations are: papillary hyperplasia, hyperpigmented hyperkeratosis, occur in the neck, axillary fossa, genitals, thighs, can also occur in the breast, glenoid fossa, back of the hand, palm, dorsal, plantar and oral, tongue, conjunctiva Sticky