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各类型结核病人均发现有不同程度的免疫抑制。临床状况的改善常伴有免疫状态的好转。左旋咪唑(左旋四咪唑,Levamisole)是一种免疫调节药物,能在很多情况下纠正免疫抑制状态。已证实此药可改进肺结核病人的白细胞植物血凝素反应过低,因而估计它能纠正结核病的免疫抑制,使之早日康复。为此作者在免疫轻度抑制的50名(男41,女9)新确诊痰菌阳性肺结核病人进行常规化疗(异烟肼300mg/日,结核胺150mg/日)及每周连续3日左旋咪唑150mg/日。另选同样比例及年龄病人50名作为对照,只进行上述抗结核化疗。病人治疗3个月,第
Various types of tuberculosis patients were found to varying degrees of immunosuppression. Improvement of clinical condition often accompanied by improvement of immune status. Levamisole (Levamisole) is an immunomodulatory drug that can correct the immunosuppressive state in many cases. This drug has been shown to improve the leukocytokidinoacid response in patients with tuberculosis and therefore it is estimated that it will correct the immunosuppression of tuberculosis and make it sooner. In this study, 50 patients (male 41, female 9) with newly diagnosed sputum positive pulmonary tuberculosis under mild immunosuppression were treated with conventional chemotherapy (isoniazid 300 mg / day and tuberculin 150 mg / day) and levamisole 150mg / day. The same proportion and age of 50 patients were selected as a control, only the above anti-TB chemotherapy. Patient treatment for 3 months, the first