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研究甲亢与甲减患者和正常人血清瘦素水平和FT3 、FT4 的关系。方法 :用放射免疫分析法测定 32例甲亢患者 ,2 8例甲减患者和 30例正常对照的血清瘦素水平。结果 :甲亢患者血清瘦素为 (9.31± 0 .2 4) μg/L ,甲减患者血清瘦素为 (4.12± 0 .15 ) μg/L ,正常对照组为 (8.83± 0 .30 ) μg/L。甲减患者血清瘦素水平明显低于甲亢组和正常对照组 (P <0 .0 1) ,而甲亢组与正常对照组无显著差异 (P >0 .5 )。结论 :甲减患者血清瘦素水平增加 ,而甲亢患者则无变化。
To study the relationship between serum leptin levels and FT3 and FT4 in hyperthyroidism and hypothyroidism patients and normal subjects. Methods: Serum leptin level was measured by radioimmunoassay in 32 patients with hyperthyroidism, 28 hypothyroidism patients and 30 normal controls. Results Serum leptin was (9.31 ± 0.24) μg / L in patients with hyperthyroidism and (4.12 ± 0.15) μg / L in patients with hypothyroidism, and (8.83 ± 0.30) μg in normal controls / L. Serum leptin level in patients with hypothyroidism was significantly lower than that in hyperthyroidism group and normal control group (P <0.01), while there was no significant difference between hyperthyroidism group and normal control group (P> 0.05). Conclusions: Serum leptin levels are increased in patients with hypothyroidism, while there is no change in patients with hyperthyroidism.