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目的观察糖尿病治疗中应用国产重组甘精胰岛素注射液与甘精胰岛素注射液(来得时)的临床治疗效果和安全性比较。方法将医院住院治疗的糖尿病患者80例作为研究对象,根据治疗方法的不同分为对照组和观察组,每组40例。对照组应用来得时进行治疗,观察组应用国产重组甘精胰岛素注射液进行治疗,对2组患者血糖情况、血糖达标时间及低血糖发生率进行观察比较。结果观察组不同时段血糖水平、低血糖发生率均低于对照组(P<0.05);观察组血糖达标时间短于对照组(P<0.05)。结论在糖尿病的治疗中,与来得时相比,国产重组甘精胰岛素注射液的临床疗效更佳,安全性更好,可在临床治疗中推广应用。
Objective To observe the clinical efficacy and safety of domestic recombinant insulin glargine injection and insulin glargine injection in the treatment of diabetes mellitus. Methods 80 hospitalized diabetic patients were divided into control group and observation group according to the different treatment methods, 40 cases in each group. The control group was used to treat the time, the observation group was treated with domestic recombinant glargine injection, and the blood glucose, blood glucose compliance time and incidence of hypoglycemia in the two groups were observed and compared. Results The blood sugar level and the incidence of hypoglycemia in the observation group were lower than those in the control group (P <0.05). The observation group had shorter blood glucose time than the control group (P <0.05). Conclusion In the treatment of diabetes mellitus, domestic recombinant insulin glargine injection has better clinical efficacy and safety than that obtained in time-lapse, and can be widely used in clinical treatment.