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目的:探讨使用丹参注射液对消化道吻合愈合的作用。方法:对260例消化道吻合术的病人,术后第1天起给予丹参注射液0.4ml/kg体重,静脉滴注,每日1次,连续用药14天,观察吻合口瘘与狭窄的发生率、检查甲皱微循环。结果:吻合口瘘与狭窄的发生率明显降低。结论:丹参可通过增加吻合口局部毛细血管开放、扩张管径、增加血流速度、改善组织液循环的作用,促进吻合口愈合并抑制吻合口瘢痕的过度增生。
Objective: To explore the effect of Danshen injection on healing of digestive tract anastomosis. Methods: 260 patients with digestive tract anastomosis were given Danshen injection 0.4ml/kg body weight from the first postoperative day, intravenous drip once daily for 14 days, anastomotic fistula and stenosis were observed. Incidence, examination of nailfold microcirculation. Results: The incidence of anastomotic leakage and stenosis was significantly reduced. Conclusion: Salvia miltiorrhiza can increase the opening of capillaries in anastomosis, expand the diameter of the caliber, increase the velocity of blood flow, and improve the function of tissue fluid circulation, promote the healing of anastomosis and inhibit the hyperplasia of anastomotic scar.