材料和方法:①深海水取自日本高知县室户海角374m深处海水,经逆向渗透去盐和浓缩。加入不同浓度的去钠水制成多种硬度的深海水。②实验选用雄性日本白兔(1.8～2.0kg)。正常白兔、胆固醇负荷兔和高脂血症模型兔均分为4组。其中1组均设为对照组,给予蒸馏水和相应饮食,其余3组分别 Materials and Methods: 1 The deep seawater was taken from seawater at a depth of 374m at Cape Muroto, Kochi Prefecture, Japan, and reversely infiltrated to remove salt and concentrate. Different concentrations of demineralized water were added to make deep seawater of various hardness. 2 Male Japanese white rabbits (1.8 to 2.0 kg) were used for the experiment. Normal white rabbits, cholesterol-loaded rabbits, and hyperlipidemia model rabbits were divided into 4 groups. One group was set as a control group and distilled water and corresponding diet were given, and the remaining 3 groups were