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为探讨表皮生长因子 (EGF)与女性不孕的关系 ,用放射免疫法测定血清、尿液、子宫内膜、宫颈粘液的 EGF。结果显示不孕组血清、尿液 EGF均明显高于对照组 (P<0 .0 0 1 ) ;不孕组子宫内膜 EGF明显低于对照组 (P<0 .0 0 1 ) ;不孕组与对照组宫颈粘液 EGF无显著性差异。说明 EGF与女性不孕症有关系 ,不孕症患者血清 EGF呈高水平 ,而子宫内膜中 EGF缺乏
To investigate the relationship between epidermal growth factor (EGF) and female infertility, the EGF of serum, urine, endometrium and cervical mucus was determined by radioimmunoassay. The results showed that the levels of EGF in serum and urine in infertility group were significantly higher than those in control group (P <0.01); the level of endometrial EGF in infertility group was significantly lower than that in control group (P0.01); infertility group There was no significant difference in cervical mucus EGF between group and control group. That EGF and female infertility have a relationship, infertility serum EGF was high, and lack of endometrial EGF