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近来研究发现,血管紧张素转换酶抑制剂(ACEI)与内皮素(ET)之间存在密切关系。ACEI能在体内外抑制自主性及分泌原刺激下的ET-1分泌,这种抑制具有极性特征,ACEI对ET-1的功能有拮抗作用。ACEI对ET的影响作用可能与肾素血管紧张素系统(R...
Recent studies have found that there is a close relationship between angiotensin-converting enzyme inhibitor (ACEI) and endothelin (ET). ACEI can inhibit autonomic and excretion of ET-1 secretion in vitro and in vivo. This inhibition is characterized by polarity. ACEI has an antagonistic effect on the function of ET-1. The effect of ACEI on ET may be related to renin angiotensin system (R ...