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目的 研究鸦胆子油乳 (简称鸦油乳 )膀胱灌注抑制膀胱癌的作用 .方法 分别以 10 0 g· L- 1 鸦油乳及 0 .4g·L- 1 丝裂霉素对膀胱癌模型 ICR小鼠行膀胱灌注 ,每周分别 1次 ,共 10次后处死 ,通过光镜及电镜观察组织结构的变化过程 .结果 灌注后两组细胞异型性不明显 ,移行上皮表面癌变征象明显减轻 ,移行上皮层次减少 ,鸦油乳细胞质内可见空泡 .结论 鸦油乳及丝裂霉素抗癌作用效果相似
Objective To study the effect of intravesical instillation of Brucea javanica oil on bladder cancer.Methods The ICR of bladder cancer model with 100 g · L -1 crowberry oil and 0 .4 g · L- The mice were instilled intravesically once a week for 10 times, then sacrificed, and the changes of tissue structure were observed by light microscope and electron microscope.Results The atherosclerosis of the two groups was not obvious, The number of epithelial cells decreased and vacuoles were found in the cytoplasm of the popliteal milk.Conclusion The anti-cancer effect of crow’s milk and mitomycin is similar