1901年Hamberger首先以牛奶蛋白耐受不良解释婴儿症状,随后出现了第1例喂牛奶后发生过敏性休克的报告,所以对牛奶过敏是在本世纪初才开始认识的。但直到1963年Goldman等建立临床标准后,牛奶过敏的诊断始广泛应用。美国约有1%婴儿对牛奶过敏,以色列估计为0.5%,故并不少见。57%发生于生后第1个月的婴儿。牛奶过敏与耐受不良系指同一疾病,有些国家用牛奶耐受不良 In 1901, Hamberger firstly explained the symptoms of infant with poorly tolerated milk protein, then the first case of anaphylactic shock after feeding milk, so allergy to milk was only recognized at the beginning of this century. However, until 1963, Goldman and other clinical standards set up, the diagnosis of milk allergy is widely used. It is not uncommon for about 1% of babies in the United States to be allergic to milk and Israel is estimated to be 0.5%. 57% occur in the first month after birth infants. Milk allergy and poor tolerance refers to the same disease, some countries with poor milk tolerance