心血管疾病(cardiovascular disease,CVD)是当今社会危害人类健康和生命最主要的疾病之一,血小板的病理性激活在CVD的发病过程中起着重要作用。微小RNA(miRNA)是一类在转录后水平调控基因表达的小分子RNA,参与多种疾病的发生发展,多种miRNA都与CVD密切相关,研究表明血小板含有丰富的miRNA,本文就血小板来源的miRNA在CVD中的作用进行综述。 Cardiovascular disease (CVD) is one of the most important diseases that endanger human health and life in today’s society. The pathological activation of platelets plays an important role in the pathogenesis of CVD. MicroRNAs (miRNAs) are small RNAs that regulate gene expression at the post-transcriptional level and are involved in the development of various diseases. Many miRNAs are closely related to CVD. Studies have shown that platelets are rich in miRNAs. In this paper, The role of miRNA in CVD is reviewed.