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本文通过各种类型的原发性青光眼共122例178只眼,对比使用包甲素和毛果芸香碱两药的降压效果.包甲素用药前后眼压差值的平均数为14毫米汞柱,毛果芸香碱为13毫米汞柱,两药均有显著降压效果(P 均<0.01),但降压值相仿(P>0.05).另外,包甲素组用药前后房水流畅系数(C 值)增加幅度为0.09,毛果芸香碱组为0.13,两药用药前后 C 值都有显著改善(P 均<0.01);但两药相互间无明显差别(P>0.05).对于急性充血性青光眼,两药也都有较好的治疗效果.因此,包甲素可以作为治疗原发性青光眼的一种良好缩瞳药物.
This article through a variety of types of primary glaucoma total of 122 cases 178 eyes, compared with the use of methotrexate and pilocarpine two drugs antihypertensive effect.Blackin treatment before and after the average intraocular pressure difference of 14 mm Hg, pilocarpine (P <0.01), but the antihypertensive values were similar (P> 0.05) .In addition, the increase of coefficient of smoothness (C value) (P <0.01), but there was no significant difference between the two drugs (P> 0.05) .For acute congestive glaucoma, both drugs also have Better therapeutic effect.Therefore, Baogan prime can be used as a good medicine for the treatment of primary glaucoma.