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目的观察奥曲肽治疗肝硬化静脉曲张破裂出血的疗效和安全性。方法采用分组对照试验,共58例,其中奥曲肽组30例;垂体后叶素28例。结果奥曲肽治疗组26例有效,总有效率86.67%,垂体后叶素组19例有效,总有效率67.86%。结论奥曲肽治疗食管静脉曲张破裂出血的疗效明显高于垂体后叶素组,且止血快、疗效肯定、不良反应少,值得在基层医院推广使用。
Objective To observe the efficacy and safety of octreotide in the treatment of patients with cirrhosis and variceal bleeding. Methods Group controlled trial, a total of 58 cases, including 30 patients with octreotide; pituitary 28 cases. Results The octreotide treatment group was effective in 26 cases, with a total effective rate of 86.67%. Pituitrin group was effective in 19 cases, with a total effective rate of 67.86%. Conclusion The efficacy of octreotide in the treatment of esophageal variceal bleeding was significantly higher than that of pituitrin group, with fast bleeding, positive curative effect and few adverse reactions. It is worth to promote the use of octreotide in primary hospital.