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目的针对二甲双胍治疗糖尿病的临床疗效进行分析探讨。方法 200例糖尿病患者作为此次研究对象,根据治疗方法的不同分为对照组(皮下注射胰岛素治疗)和实验组(口服二甲双胍治疗),每组100例,对两组患者的治疗效果进行分析观察。结果实验组治疗总有效率99.0%明显高于对照组92.0%,差异具有统计学意义(P<0.05)。治疗后,两组患者的空腹血糖、餐后2 h血糖及糖化血红蛋白比较差异均无统计学意义(P>0.05);对照组患者使用胰岛素的剂量明显高于实验组,差异具有统计学意义(P<0.05)。实验组不良反应发生率3.0%低于对照组12.0%,差异具有统计学意义(P<0.05)。结论二甲双胍治疗糖尿病具有效果好、不良反应少的优势,值得推广使用。
Objective To investigate the clinical efficacy of metformin in the treatment of diabetes mellitus. Methods 200 diabetic patients were divided into control group (subcutaneous insulin treatment) and experimental group (oral metformin treatment) according to the different treatment methods. The patients in each group were treated with metformin 100 cases. The therapeutic effect of the two groups was analyzed . Results The total effective rate of experimental group was 99.0%, which was significantly higher than that of control group (92.0%) (P <0.05). After treatment, there was no significant difference in fasting blood glucose, postprandial 2-h blood glucose and HbA1c in both groups (P> 0.05). The dosage of insulin in the control group was significantly higher than that in the experimental group P <0.05). The incidence of adverse reactions in the experimental group was 3.0% lower than that in the control group (12.0%), the difference was statistically significant (P <0.05). Conclusion Metformin treatment of diabetes with good effect, fewer adverse reactions, it is worth promoting the use of.