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目的:对比研究老年社区获得性肺炎患者分别使用替加环素与左氧氟沙星联合阿奇霉素的治疗效果。方法:将深圳南山2013年1月至2014年12月确诊的老年社区获得性肺炎患者200例随机分为对照组(n=100)和研究组(n=100),对照组接受阿奇霉素联合左氧氟沙星,研究组接受替加环素治疗,比较两组的临床疗效。结果:研究组中痊愈或显效93例,总有效率是93%,无效有7例;对照组中显效或痊愈83例,总有效率是83%,无效17例,研究组的总有效率明显高于对照组,差异有统计学意义(P<0.05)。结论:与阿奇霉素联合左氧氟沙星相比,使用替加环素治疗老年社区获得性肺炎患者的效果更好,且不良反应发生率少,建议临床考虑使用。
OBJECTIVE: To compare the effects of tigecycline and levofloxacin in combination with azithromycin in elderly patients with community-acquired pneumonia. Methods: A total of 200 elderly patients with community-acquired pneumonia diagnosed in Shenzhen Nanshan from January 2013 to December 2014 were randomly divided into control group (n = 100) and study group (n = 100). The control group received azithromycin combined with levofloxacin, Study group received tigecycline treatment, the clinical efficacy of the two groups were compared. Results: The study group, 93 cases were cured or markedly effective, the total effective rate was 93%, 7 cases were ineffective; effective or cured 83 cases in the control group, the total effective rate was 83%, 17 cases ineffective, the total effective rate was significantly Higher than the control group, the difference was statistically significant (P <0.05). Conclusion: Compared with azithromycin and levofloxacin, the use of tigecycline in elderly patients with community-acquired pneumonia is better, and the incidence of adverse reactions less recommended for clinical use.