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目的研究探讨地屈孕酮治疗先兆流产的应用效果。方法选取我院2015年11月~2016年11月门诊常规收治的90例先兆流产患者,根据统计学随机匹配法将患者均分为45例第一组和45例第二组,第一组患者使用黄体酮注射液进行治疗先兆流产,而第二组则使用口服型地屈孕酮片。根据两组患者的症状变化及胚胎的发育状态进行评价治疗效果。结果第二组患者的先兆流产症状治疗成功率为97.78%(44/45)高于第一组患者的82.22%(37/45),统计学检验分析显示两组间成功率的比较,差异有统计学意义(P<0.05);而且第一组用药后不良反应的发生明显多于第二组,差异有统计学意义(P<0.05)。结论地屈孕酮治疗先兆流产的安全性良好,其临床应用成功率较高,对继续妊娠过程无严重影响,值得对出现先兆流产症状的孕妇尽早应用此药治疗。
Objective To study the application effect of dydrogesterone in the treatment of threatened abortion. Methods 90 cases of threatened abortion routinely treated in the outpatient department from November 2015 to November 2016 in our hospital were selected and randomly divided into 45 cases in the first group and 45 cases in the second group. The patients in the first group The use of progesterone injection for the treatment of threatened abortion, while the second group is the use of oral progesterone tablets. According to two groups of patients with symptoms and embryonic development status to evaluate the therapeutic effect. Results The success rate of symptomatic treatment for threatened abortion in the second group was 97.78% (44/45), which was higher than that in the first group (82.22%, 37/45). The statistical analysis showed that there was a significant difference in the success rates between the two groups Statistical significance (P <0.05); and the first group of adverse reactions after treatment was significantly more than the second group, the difference was statistically significant (P <0.05). Conclusions Dydrogesterone is a safe treatment for threatened abortion, with a high success rate of clinical application and no serious impact on the process of continuing pregnancy. It is worthwhile to apply the drug to pregnant women with symptoms of threatened abortion as early as possible.