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目的研究2型糖尿病下肢周围神经病变患者采用甲钴胺配合中药方(自拟化湿活血汤)治疗的效果。方法任选在该院治疗的2型糖尿病下肢周围神经病变患者60例,选取时间跨度为2015年7月—2016年7月,采用数字随机的方法将60例患者均分2组(对照组=30例,给予常规治疗方法;研究组=30例,给予自拟化湿活血汤配合甲钴胺治疗方法),并对最终的治疗效果进行分析和对比。结果治疗后,研究组神经系统症状评分(4.2±0.2)分、密西根MDNS评分(5.4±0.4)分、不良反应发生率9.38%等指标均优于对照组(6.7±1.3)分、(8.6±1.6)分、30.0%(P<0.05)。结论对2型糖尿病下肢周围神经病变患者采用自拟化湿活血汤配合甲钴胺治疗,效果显著,患者各项指标改善情况良好,该方法值得大力推广。
Objective To study the effect of mecobalamin combined with traditional Chinese medicine (self-made Huashi Huoxue Decoction) in the treatment of lower extremity peripheral neuropathy in type 2 diabetic patients. Methods Sixty patients with type 2 diabetes mellitus and peripheral neuropathy who were treated in this hospital were randomly selected from July 2015 to July 2016. All patients were divided into two groups randomly (control group = 30 cases, given conventional treatment; study group = 30 cases given self-made Huashi Huoxue Decoction with mecobalamin treatment), and the final treatment effect analysis and comparison. Results After treatment, the scores of neurological symptoms (4.2 ± 0.2), MDNS (5.4 ± 0.4) in Michigan and 9.38% of adverse reactions in the study group were significantly better than those in the control group (6.7 ± 1.3) and (8.6 ± 1.6), 30.0% (P <0.05). Conclusion The treatment of lower extremity peripheral neuropathy in type 2 diabetes patients with self-made Huashi Huoxue Decoction combined with methylcobalamin treatment, the effect is significant, the patient improved in good condition, the method deserves to be promoted.