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近年来在眼科和神经科临床诊断中广泛应用了图形翻转皮层视觉诱发电位(VEP)的测定。常用的诊断参数是P_(100)波的振幅和潜伏期(亦称P_1波)。其中潜伏期在视路疾患诊断中是一项敏感指标。P_(100)波的振幅和潜伏期受年龄、电极位置、刺激参数、屈光状态和刺激野等诸多为素的影响。其中屈光状态的影响往往不被重视,因而造成假阳性。本文通过给予不同屈光负荷测定VEP、P_(100)波振幅和潜伏期的变化,证实矫正屈光对获得正确VEP的必要性。
In recent years in the clinical diagnosis of ophthalmology and neurology widely used visual cortex flip-flop visual evoked potential (VEP) determination. Common diagnostic parameters are amplitude and latency of P_ (100) waves (also known as P_1 waves). Including latency in the diagnosis of visual pathology is a sensitive indicator. The amplitude and latency of P_ (100) wave are influenced by age, electrode position, stimulation parameters, refractive status and stimulation field. The effects of refractive status are often not taken seriously, resulting in false positives. In this paper, the changes of VEP, P_ (100) wave amplitudes and latency were determined by different refractive loads, and the necessity of correcting refractive errors to obtain the correct VEP was confirmed.