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目的探讨甲基强的松龙联合硫酸镁治疗重症支气管哮喘的临床疗效。方法 42例重症支气管哮喘患者,对患者进行甲基强的松龙联合硫酸镁治疗,观察治疗前后患者的肺功能变化情况,对整体临床疗效进行评价。结果治疗后患者的用力肺活量(FVC)、最大呼吸流量(PEF)和一秒钟用呼吸容积(FEV1)指标较治疗前有所改善,差异有统计学意义(P<0.05),治疗后患者的心功能得到了显著改善,治疗总有效率为95.2%。结论甲基强的松龙联合硫酸镁治疗重症支气管哮喘的疗效确切,值得临床进一步推广使用。
Objective To investigate the clinical efficacy of methylprednisolone and magnesium sulfate in the treatment of severe bronchial asthma. Methods Forty - two patients with severe bronchial asthma were treated with methylprednisolone and magnesium sulfate. The changes of pulmonary function before and after treatment were observed and the overall clinical efficacy was evaluated. Results After treatment, the FVC, PEF and FEV 1 of the patients after treatment were improved compared with before treatment, the difference was statistically significant (P <0.05). After treatment, the patients’ Heart function has been significantly improved, the total effective rate was 95.2%. Conclusion Methylprednisolone combined with magnesium sulfate in the treatment of severe bronchial asthma is effective and worthy of further clinical use.