国际杂志《Circulation Research》在线发表了北京大学分子医学所何爱彬研究组题为“Divergent requirements for EZH1 in heart development versus regeneration”的研究成果。研究揭示同一表观调控因子EZH1在心脏发育和再生过程中,产生不同的组蛋白修饰,导致截然不同的分子机制,调控发育与再生两个关联的生物学过程。该结果为心脏再生的临床治疗策略提供了新的 The international journal Circulation Research publishes the research report by He Aibin Research Group, Institute of Molecular Medicine, Peking University, entitled “Divergent requirements for EZH1 in heart development versus regeneration.” The study revealed that the same apparent regulatory factor EZH1 produces different histone modifications during cardiac development and regeneration, resulting in distinct molecular mechanisms that regulate the biological processes associated with development and regeneration. This result provides a new therapeutic strategy for cardiac regeneration