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患者,女,36岁,因咽痛、咳嗽,自服头孢拉定0.5g。约40分钟后,从头面部开始逐渐至全身瘙痒,皮肤发红,头晕、恶心、呕吐胃内容物1次,继之出现胸闷、心悸、出汗,四肢发冷,随急来我院。查体:意识恍惚,面色苍白,口唇发绀,血压60/45mmHg,心率58次/分。立即给予吸氧,肾上腺素,地塞米松,低分子右旋糖酐、多巴胺等对症处理。约30分钟患者血压升至100/60mmHg,心率80次/分,律齐,1小时后症状消失。追问病史:一年前因感冒后服用头孢拉定后出现皮肤发痒,轻度胸闷、心悸等,当时未经治疗,自行缓解。 讨论:患者服用头孢拉定后约40分钟出现头晕、胸闷、心悸、四肢发冷、口唇发绀、呼吸困难及血
Patients, female, 36 years old, due to sore throat, cough, self serving cephradine 0.5g. About 40 minutes later, from the head and face began to gradually systemic itching, redness, dizziness, nausea, vomiting stomach contents 1, followed by chest tightness, palpitations, sweating, cold limbs, with emergency to our hospital. Examination: Consciousness, pale, lips cyanosis, blood pressure 60 / 45mmHg, heart rate 58 beats / min. Immediately given oxygen, epinephrine, dexamethasone, low molecular weight dextran, dopamine symptomatic treatment. About 30 minutes the patient’s blood pressure rose to 100 / 60mmHg, heart rate 80 beats / min, law Qi, 1 hour after the symptoms disappear. History: a year ago due to cold after taking cephradine appeared itchy skin, mild chest tightness, palpitations, etc., then untreated, relieve themselves. Discussion: About 40 minutes after taking cephradine, the patient developed dizziness, chest tightness, palpitations, cold extremities, cyanosis of the lips, difficulty breathing and blood