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我们测定了武汉市77例高血压病患者头发中12种元索的含量,与36例正常对照组比较,高血压病Ⅰ、Ⅱ、Ⅲ期患者皆有锌、钙、镁显著降低,铅显著增高;Ⅱ、Ⅲ期患者铬、镍均显著降低;Ⅲ期患者还有铜、钴显著降低,锰、铁显著增高。按中医辨证理论将高血压病Ⅰ、Ⅱ期患者分为肝肾阴虚、肝阳上亢两组,前者钙、镁、钴含量显著高于后者,而铁、镍显著低于后者。我们认为头发元素含量的变化与高血压病发生及其演变有关,并且为中医辨证施治理论提供了物质基础。
We measured the content of 12 kinds of methotrexate in the hair of 77 patients with essential hypertension in Wuhan. Compared with 36 normal controls, the levels of zinc, calcium and magnesium in patients with stage I, II and III of hypertension were significantly decreased Increased in grade II and III patients, while the levels of chromium and nickel in patients in stage III and III were significantly lower. The levels of copper and cobalt in patients in stage III were significantly decreased while the contents of manganese and iron were significantly increased. According to TCM theory, patients with stage I and II of hypertension were divided into two groups: liver and kidney yin deficiency and hyperactivity liver yang. The contents of calcium, magnesium and cobalt in the former were significantly higher than those in the latter, while the contents of iron and nickel were significantly lower than those in the latter. We believe that the change of the content of hair elements is related to the occurrence and development of hypertension and provides the material basis for TCM syndrome differentiation and treatment theory.