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目的探讨冠心病和慢性牙周炎之间的相关性。方法选取我院2009年1月至2011年1月我院收治的冠心病患者275例作为冠心病组,健康体检患者236例作为对照组,比较两组患者的一般资料、牙周指标,进行多因素logistic回归分析,随访患者1年和5年的牙周指标。结果冠心病组高血压率、吸烟率、TG、HDL-C、WBC和FG高于对照组(P<0.05);1年后,冠心病组PD、CAL和PI均高于对照组(t=2.75,P<0.01;t=2.46,P<0.05;t=3.75,P<0.01);5年后,冠心病组PD、CAL和PI均高于对照组(t=2.75,P<0.05;t=2.46,P<0.05;t=3.75,P<0.05);冠心病组慢性牙周炎率显著高于正常组(χ~2=6.81,P<0.01);轻度、中度和重度牙周炎患者中,急性冠脉综合征发病率均显著高于劳累性心绞痛发病率(χ~2=6.06,P<0.05;χ~2=8.82,P<0.05;χ~2=4.34,P<0.05);慢性牙周炎为冠心病的独立危险因素。结论冠心病和慢性牙周炎存在一定的关联,两者可相互影响。
Objective To explore the correlation between coronary heart disease and chronic periodontitis. Methods From January 2009 to January 2011 our hospital admitted to our hospital 275 cases of coronary heart disease patients as coronary heart disease group, 236 healthy patients as control group, comparing the two groups of patients with general information, periodontal indicators, more Factors of logistic regression analysis, follow-up of patients with 1-year and 5-year periodontal indicators. Results The rates of hypertension, smoking, TG, HDL-C, WBC and FG in CHD group were higher than those in control group (P <0.05). After 1 year, the PD, CAL and PI in CHD group were higher than those in control group (t = (P> 0.05); t = 2.46, P <0.05; t = 3.75, P <0.01); After 5 years, the PD, CAL and PI in CHD group were higher than those in control group = 2.46, P <0.05; t = 3.75, P <0.05). The rate of chronic periodontitis in CHD group was significantly higher than that in normal group (χ ~ 2 = 6.81, P <0.01) The incidence of acute coronary syndrome was significantly higher in patients with inflammation than in patients with exertional angina (χ ~ 2 = 6.06, P <0.05; χ ~ 2 = 8.82, P <0.05; ); Chronic periodontitis is an independent risk factor for coronary heart disease. Conclusion Coronary heart disease and chronic periodontitis are related to each other, and the two can affect each other.