为了验证在无并发症的败血症中凝血系统和血小板被激活的假设,并与严重败血症和败血性休克时的情况进行比较,对74例败血症患者(45例为败血症,15例为严重败血症,14例为败血性休克)和14例健康志愿者血液中凝血因子、凝血系统激活和血小板激活的分子标志物以及血小板计数和凝血时间进行了测定。结果显示,与健康者相比,败血症患者凝血酶原片断1和2(F1+2)、纤维蛋白肽A(FPA)、凝血酶-抗凝血酶复合体 In order to verify the hypothesis that the coagulation system and platelets are activated in uncomplicated sepsis and compared with those in severe sepsis and septic shock, 74 sepsis patients (45 sepsis, 15 severe sepsis, 14 Cases of septic shock) and blood coagulation factors in 14 healthy volunteers, coagulation system activation and platelet activation markers and platelet count and clotting time was measured. The results showed that prothrombin fragments 1 and 2 (F1 + 2), fibrinopeptide A (FPA), thrombin-antithrombin complex