慢性肾脏疾病(CKD)是目前临床常见疾病且还没有很好的治疗方法。维生素D(VitD)类似物广泛用于CKD相关的骨和钙磷代谢障碍疾病。然而,越来越多的研究表明,VitD类似物除对骨和矿质代谢的经典作用外,可能还存在其他作用。本文主要综述了VitD类似物在CKD中的抗蛋白尿和肾保护作用以 Chronic kidney disease (CKD) is a common clinical disease and there is no good treatment. Vitamin D (VitD) analogs are widely used in CKD-related disorders of bone and calcium and phosphorus metabolism. However, a growing body of research suggests that VitD analogs may have other effects besides their classical role in bone and mineral metabolism. This article reviews the anti-proteinuria and renal protection of VitD analogues in CKD