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目的:探讨参麦注射液对创伤性休克早期液体复苏患者效果观察及对血氧饱和度和血液流变学指标水平的影响。方法:按照随机数字表法将本组纳入的82例患者随机分为观察组(n=46)和对照组(n=46)。对照组采用常规治疗,观察组在对照组基础上结合参麦注射液治疗。观察两组血压、脉搏、无创血氧饱和度、尿量及血液流变学水平。结果:观察组治疗1 h、2 h、3 h血压和无创血氧饱和度显著高于对照组,脉搏显著低于对照组,且均具有显著性意义(P<0.05);观察组治疗1 h、治疗2 h、治疗3 h尿量均显著多于同期对照组,且均具有显著性意义(P<0.05);两组治疗2 h、治疗3 h尿量显著多于同组治疗1 h,且均具有显著性意义(P<0.05);两组治疗3 h尿量显著多于同组治疗2 h,且具有显著性意义(P<0.05);观察组治疗后血红蛋白浓度、红细胞比容、血小板含量显著高于对照组,且均具有显著性意义(P<0.05)。结论:参麦注射液对创伤性休克早期液体复苏患者效果显著,可明显改善患者血氧饱和度和血液流变学水平,尤其适用于创伤性休克早期液体复苏,具有重要临床意义。
Objective: To investigate the effect of Shenmai injection on early liquid resuscitation in traumatic shock and its effect on the level of blood oxygen saturation and hemorheology. Methods: According to the random number table, 82 patients included in this study were randomly divided into observation group (n = 46) and control group (n = 46). The control group with conventional treatment, the observation group on the basis of the control group combined with shenmai injection. Blood pressure, pulse, non-invasive oxygen saturation, urine output and hemorheology were observed. Results: The blood pressure and non-invasive oxygen saturation of observation group were significantly higher than those of control group at 1 h, 2 h and 3 h, and the pulse rate of observation group was significantly lower than that of control group (P <0.05) , 2 h treatment, 3 h urine output were significantly more than the same period the control group, and have significant significance (P <0.05); 2 h treatment 2 h, 3 h urine output was significantly more than the same treatment 1 h, (P <0.05). The urinary output in 3 h after treatment in both groups was significantly higher than that in the same group for 2 h (P <0.05). After treatment, the hemoglobin concentration, hematocrit, The platelet content was significantly higher than that of the control group (P <0.05). Conclusion: Shenmai injection has significant effect on early liquid resuscitation in patients with traumatic shock, which can significantly improve blood oxygen saturation and hemorheology, especially for early liquid resuscitation of traumatic shock, which has important clinical significance.