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目的:探讨口服糖皮质激素治疗慢性阻塞性肺病急性加重期的临床疗效。方法:2012年2月-2014年2月收治慢性阻塞性肺病急性加重期患者100例,均在氧疗、祛痰、支气管扩张剂、抗生素治疗的基础上口服强的松30mg/日进行治疗,疗程7天。结果:PaCO2治疗前(69.43±4.13)mmHg,治疗后(41.87±4.45)mmHg;PaO2治疗前(51.06±6.01)mmHg,治疗后(76.72±5.92)mmHg。治疗前后比较差异有统计学意义(P<0.05)。结论:口服糖皮质激素可以迅速提高慢性阻塞性肺病急性加重期的血氧饱和度,临床疗效显著,值得推广。
Objective: To investigate the clinical efficacy of oral glucocorticoid in the treatment of acute exacerbation of chronic obstructive pulmonary disease. Methods: From February 2012 to February 2014, 100 patients with acute exacerbation of chronic obstructive pulmonary disease were treated with oral prednisone 30mg / day on the basis of oxygen therapy, expectorant, bronchodilator and antibiotic therapy, Treatment for 7 days. Results: PaCO2 before treatment (69.43 ± 4.13) mmHg, after treatment (41.87 ± 4.45) mmHg; PaO2 before treatment (51.06 ± 6.01) mmHg, after treatment (76.72 ± 5.92) mmHg. Before and after treatment, the difference was statistically significant (P <0.05). Conclusion: Oral corticosteroids can rapidly increase the blood oxygen saturation in patients with acute exacerbation of chronic obstructive pulmonary disease. The clinical effect is significant and worthy of promotion.