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遵照伟大领袖毛主席关于“中国医药学是一个伟大的宝库,应当努力发掘,加以提高”的教导,走中西医结台的道路,我科血液组及附院血液室为寻找抗白血病的有效中草药,自1976.3—1977.4釆用美兰试管法筛选了70种中草药,现将初步结果报告如下: 一、美兰试管法药物筛选试验的原理肿瘤和白血病细胞一个最突出的代谢特征,就是它们具有高度的糖酵解活性,以致大量产生乳酸。与此相关连的一些脱氢酶活力,例如乳酸脱氢酶活力,在肿瘤和白血病细胞中亦显著提高。抗白血病药物杀灭白血病细胞或抑制其酵解活性时,往往引起脱
Following the teachings of Chairman Mao, the great leader, on “Chinese medicine is a great treasure trove, we should make every effort to find and improve it” and follow the path of Chinese and Western medicine. The blood group of our department and the blood room of the subsidiary hospital look for effective Chinese herbal medicine against leukemia , From 1976.3-1977.4 preclude the use of Melanie tube screening of 70 kinds of Chinese herbal medicine, the preliminary results are reported as follows: First, the principle of the Melanie test tube drug screening test One of the most prominent metabolic features of cancer and leukemia cells is that they have a high degree of Glycolytic activity, resulting in the production of lactic acid in large quantities. Some dehydrogenase activity associated with this, such as lactate dehydrogenase activity, is also significantly increased in tumor and leukemia cells. Anti-leukemia drugs kill leukemia cells or inhibit their glycolysis activity, often leading to off