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目的了解山东省鲁西北地区地方性氟中毒的流行现状,为制定防制策略提供科学依据。方法选择山东省鲁西北地区11个县进行水、人尿氟含量测定、8～12岁儿童氟斑牙诊断及临床和X线摄片检查氟骨症调查。结果在11个县调查17个改水村,水氟均值≤1.00 mg/L的村12个,占70.59%(12/17);>1.00 mg/L的村5个,占29.41%(5/17);水氟最大值为4.46 mg/L;调查16个未改水村,水氟均值≤1.00 mg/L的村5个,占31.25%(5/16);>1.00 mg/L的村11个,占68.75%(11/16),水氟最大值为4.09 mg/L;8～12岁儿童氟斑牙总患病率为51.51%(701/1 361),氟斑牙指数为1.05,缺损率为6.25%(85/1 631);儿童尿氟均值在>1.40 mg/L的占60.86%(510/838),最高值为15.20 mg/L;>16岁成人的氟骨症临床和X线检出率分别为2.49%(454/18 257),15.79%(3/19);成人尿氟均值在>1.60 mg/L的占62.27%(406/652),最高值为25.44mg/L。结论山东省鲁西北地区地方性氟中毒病情尚未得到有效的控制,防制形势依然比较严峻,须进一步加大防制力度。
Objective To understand the prevalence of endemic fluorosis in the northwest of Shandong Province and to provide a scientific basis for the formulation of prevention and control strategies. Methods Eleven counties in northwestern Shandong Province were selected for the determination of fluorine and fluoride in children and children aged from 8 to 12 years. The fluorosis was investigated by clinical and radiographic examination. Results In 11 counties, 12 villages (17.59% (12/17)) whose water fluoride mean was ≤1.00 mg / L were surveyed and 17 villages (> 29.41%) were villages with> 1.00 mg / L ); The maximum value of water fluoride was 4.46 mg / L; 5 of the 16 unimproved water villages, 31.25% (5/16) of the villages with water fluoride mean value ≤1.00 mg / L and 11 villages> 1.00 mg / L , Accounting for 68.75% (11/16) and the maximum value of water fluoride was 4.09 mg / L. The total prevalence of dental fluorosis was 51.51% (701/1 361) in children aged 8-12 years, and the dental fluorosis index was 1.05 The rate of urinary fluoride in children was> 1.40 mg / L, accounting for 60.25% (510/838), the highest was 15.20 mg / The detection rates were 2.49% (454/18 257) and 15.79% (3/19), respectively. The urinary fluoride mean of adults was 62.27% (406/652) at> 1.60 mg / L and the highest value was 25.44 mg / L . Conclusion The endemic fluorosis in the northwest of Shandong Province has not been effectively controlled and the situation of prevention and control is still relatively severe. Therefore, the intensity of prevention and control should be further strengthened.