冠状动脉痉挛(CAS)早在十八世纪末(1792年) 国外学者已经提出,但当时没有客观依据,未能得到承认。到本世纪五十年代末(1959年),国外学者注意到有一些心绞痛病人不是在白天劳累后发作,而是在夜间休息时发作,发作时心电图ST段不是下降而是抬高,并认为与CAS有关,故称之为颠倒型心绞痛,不久 Coronary artery spasm (CAS) as early as the end of the eighteenth century (1792) foreign scholars have already made, but there was no objective basis, failed to be recognized. By the late fifties of this century (1959), foreign scholars noticed that some patients with angina pectoris did not attack during the day after exertion, but at rest during the night. ST-segment electrocardiography was not decreased but elevated at the time of attack, CAS related, it is called inverted angina, soon