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目的比较年龄<40岁与≥40岁新诊断T2DM患者心血管病变(CVD)危险因素水平及聚集情况。方法选取既往无冠心病病史的新诊断T2DM患者568例,分为年龄<40岁组136例和年龄≥40岁组432例,收集一般资料和主要病史等,检测血糖、血脂、HbA1c、高敏C反应蛋白(hsC-RP)和24hUAlb等指标。结果年龄<40岁组BMI、BP、血糖、血脂、HbA1c、hsC-RP、24hUAlb、吸烟、CVD家族史、肥胖/超重、BP升高、血脂异常、蛋白尿阳性率以及合并不同CVD危险因素数量的发生率与年龄≥40岁组比较差异无统计学意义,但血脂异常、BP升高的病情知晓率及治疗率低于年龄≥40岁组(P<0.01)。结论年龄<40岁与≥40岁新诊断T2DM患者具有相似的CVD发生风险,但前者病情知晓率及治疗率更低。
Objective To compare the risk factors of cardiovascular disease (CVD) in newly diagnosed T2DM patients aged <40 years and ≥40 years. Methods A total of 568 newly diagnosed T2DM patients without a history of coronary heart disease were enrolled in this study. One hundred and sixty-six patients with age <40 years and 432 cases with age ≥40 years old were enrolled in this study. General data and major medical history were collected. Blood glucose, blood lipid, HbA1c, Reactive protein (hsC-RP) and 24hUAlb and other indicators. Results BMI, BP, blood glucose, blood lipid, HbA1c, hsC-RP, 24hUAlb, smoking, family history of CVD, obesity / overweight, BP increased, dyslipidemia, proteinuria positive rate and the number of different CVD risk factors The incidence of dyslipidemia and BP was significantly lower than that of patients aged 40 years or older (P <0.01). Conclusions There is a similar risk of CVD in newly diagnosed T2DM patients aged <40 years and ≥40 years, but the former has a lower rate of awareness and treatment.