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采用药理学方法,结合乙醛酸诱发儿茶酚胺(CA)荧光技术,研究了家兔静脉快速注射BaCl2(7mg/kg)诱发包括心室颤动在内的严重室性心律失常的机制.结果提示:BaCl2诱发的室性心律失常与内源性CA释放激动肾上腺素能α-受体有关.
Pharmacological methods combined with glyoxylate-induced catecholamine (CA) fluorescence were used to study the mechanism of intravenous bolus injection of BaCl2 (7 mg / kg) in rabbits to induce severe ventricular arrhythmia including ventricular fibrillation. The results suggest that BaCl2-induced ventricular arrhythmias are associated with the release of agonistic adrenergic alpha-receptors by endogenous CA.