论文部分内容阅读
应用双抗体夹心ＥＬＩＳＡ法、３Ｈ－ＴｄＲ掺入法和１２５Ｉ－ＵｄＲ释放法对２４例鼻咽癌（ＮＰＣ）患者ＹＡＧ激光汽化结合光动力学治疗前后外周血可溶性ＩＬ－２受体（ＳＩＬ－２Ｒ）、白细胞介素２（ＩＬ－２）水平和自然杀伤细胞（ＮＫ）活性分别进行测定。结果表明鼻咽癌患者在接受激光光动力学治疗后ＳＩＬ－２Ｒ水平呈明显下降（Ｐ＜０．０００５），而ＩＬ－２水平和ＮＫ活性显著上升（Ｐ＜０．０００５）。结果提示激光光动力学治疗对恢复鼻咽癌患者免疫功能起促进作用。
Twenty-four patients with nasopharyngeal carcinoma (NPC) were treated with YAG laser vaporization combined with peripheral blood soluble IL-2 receptor (SIL-2R) before and after photodynamic therapy with double antibody sandwich ELISA, 3H-TdR incorporation and 125I- ), Interleukin 2 (IL-2) and natural killer (NK) activity were measured. The results showed that SIL-2R level was significantly decreased in patients with nasopharyngeal carcinoma after laser photodynamic therapy (P <0.0005), while IL-2 level and NK activity were significantly increased (P <0.0005). The results suggest that laser photodynamic therapy can promote the recovery of immune function in patients with nasopharyngeal carcinoma.