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通过对３４名布病１０４Ｍ菌苗免疫的重点职业人群血清抗体水平跟踪观察结果表明，菌苗免疫后的血清抗体呈正常消涨趋势，说明机体已产生相应的抗体，具有抵抗感染布病的免疫能力，因此，有必要对密切接触布病传染源的职业人群，进行每年一次的预防接种工作。
The results of the follow-up observation of serum antibody levels in key occupational groups immunized against 34 brucellosis 104M vaccines showed that the serum antibodies after the vaccine immunization showed a normal trend of decline, indicating that the body has produced the corresponding antibodies and has the immunity against brucellosis Therefore, it is necessary to conduct an annual vaccination work for occupational groups closely contacted with the source of the brucellosis.