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目的 研究形觉剥夺对眼球发育及屈光状态的影响 ,探讨近视眼发病机理及近视发生的危险因素。方法 对一组单眼患早期形觉剥夺性眼病患者的眼球各屈光因子 ,进行生物学测量比较 ,确定其屈光状态 ,并用t检验及多元相关分析的方法找出形觉剥夺性近视的危害因子。结果 患眼与健眼相比 ,患眼有较明显的近视倾向 ,平均屈光力相差 1 2 0 1D。两组比较角膜屈光力、晶状体厚度差异无显著性意义 ;前房深度、玻璃体腔长度、眼轴长度、眼的屈光状态差异均具有显著性意义。玻璃体腔长度为近视眼发生的主要危险因素。结论 早期形觉剥夺可发生近视眼 ,其主要危险因子是眼轴长度 ,主要危害部位在眼后段。尽早去除形觉剥夺 ,保持或恢复视觉发育敏感期的正常视觉环境 ,有利于预防近视眼的发生。
Objective To study the influence of form deprivation on eye development and refractive status and explore the pathogenesis of myopia and the risk factors of myopia. Methods A group of monocular patients with early form deprivation eye disease in the refractive index of each eye, biological measurements were compared to determine the refractive status, and t-test and multivariate correlation analysis to identify the risk of form-deprivation myopia factor. Results Compared with healthy eyes, the affected eyes had obvious tendency of myopia with a mean refractive power of 1201D. There was no significant difference between the two groups in corneal refractive power and lens thickness. There was significant difference in anterior chamber depth, vitreous cavity length, axial length and refractive status of eyes. The length of the vitreous cavity is the main risk factor for myopia. Conclusion Early shape deprivation may occur myopia, the main risk factor is axial length, the main damage in the posterior segment of the eye. As soon as possible to remove the deprivation of form, maintain or restore the normal visual development of sensitive visual environment, is conducive to the prevention of myopia.