脂质过氧化(Lipid peroxidation,简称LPO)过程可由自由基和一些氧化剂所引发,在此过程中可由不饱和脂肪酸产生多种脂质过氧化产物。脂质过氧化物再二次分解产生低级烃类,如乙烷、戊烷等。关于利用气相色谱法测定低级烃类以研究LPO与医学的关系,国外已有不少报道,但在国内起步较晚。本文简要介绍呼出气中低级烃类的气相色谱法测定及其应用,以供参考。 Lipid peroxidation (LPO) process can be initiated by free radicals and some oxidants, in the process can produce a variety of lipid peroxidation products from unsaturated fatty acids. Lipid peroxide re-decomposes to lower hydrocarbons such as ethane, pentane and the like. On the use of gas chromatography to determine the relationship between low-grade hydrocarbons and LPO medicine, foreign reports have been many, but started late in China. This article briefly describes the gas expiration of lower hydrocarbons by gas chromatography and its application, for reference.