论文部分内容阅读
目的:探讨液基超薄细胞技术(thinp rep cytologic test,TCT)和Bethesda系统(TBS)在早期宫颈病变诊断中的临床价值。方法:对2007年3月~2009年3月在十堰市妇幼保健院就诊的9 000例患者进行TCT检查和TBS细胞学分类诊断,对TCT的检查发现异常的患者进行阴道镜病理检查。结果:9 000例涂片中检出异常涂片452例(5.02%),其中典型鳞状细胞(ASC)187例(2.08%),低度鳞状上皮内病变(LSIL)200例(2.20%),高度鳞状上皮内病变(HSIL)41例(0.46%),鳞状细胞癌(SCC)3例(0.03%)。30~39岁年龄段,异常涂片最高178例(39.38%),其次是40~49岁年龄段126例(27.88%),与其他年龄组相比差异有统计学意义(P<0.05)。TCT与病理检查符合率分别为LSIL71.00%、HSIL94.00%、SCC100%,两者比较差异无统计学意义。结论:TCT技术结合TBS应用于宫颈细胞涂片配合阴道镜活检,是筛查和诊断子宫颈癌前病变的可靠手段,在降低宫颈癌发病率及死亡率方面起重要作用,为宫颈癌防治打下坚实的基础。
Objective: To investigate the clinical value of thinp rep cytologic test (TCT) and Bethesda system (TBS) in the diagnosis of early cervical lesions. Methods: From March 2007 to March 2009, 9 000 patients treated in Shiyan MCH hospital were diagnosed by TCT and TBS cytology, and colposcopy pathological examination was performed on patients with abnormal TCT examination. Results: A total of 452 cases (5.02%) were detected in 9 000 smears, including 187 cases of typical squamous cell carcinoma (ASC), 200 cases of low grade squamous intraepithelial lesion (LSIL) (2.20% ), High grade squamous intraepithelial lesions (HSIL) in 41 cases (0.46%) and squamous cell carcinoma (SCC) in 3 cases (0.03%). In the age group of 30-39 years, abnormal smear was the highest in 178 cases (39.38%), followed by 126 cases (27.88%) in the age group of 40-49 years, with statistical significance compared with other age groups (P <0.05). The coincidence rates of TCT and pathology were LSIL71.00%, HSIL94.00% and SCC100%, respectively, with no significant difference between the two. Conclusion: TCT combined with TBS in cervical smears combined with colposcopy biopsy is a reliable method to screen and diagnose cervical precancerous lesions, plays an important role in reducing the incidence and mortality of cervical cancer and laying a foundation for the prevention and treatment of cervical cancer solid foundation.