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目的探讨腹腔温热灌注化疗在胃癌根治术中的应用。方法2004年4月～2007年8月本院收治的进展期胃癌手术病人71人,随机分为腹腔温热灌注化疗组39人和生理盐水灌洗组32人,分别检查各组手术前及灌洗后腹腔脱落癌细胞。结果手术前两组腹腔脱落癌细胞无明显差异;灌洗后,温热灌注化疗组腹腔脱落癌细胞检出率明显低于生理盐水灌洗组。结论腹腔温热灌注化疗在进展期胃癌术中是安全、有效的。
Objective To investigate the application of intraperitoneal hyperthermic perfusion chemotherapy in radical resection of gastric cancer. Methods From April 2004 to August 2007, 71 patients with advanced gastric cancer who were treated in our hospital were randomly divided into three groups: 39 in peritoneal hyperthermic perfusion group and 32 in saline lavage group. Abdominal cavity after washing shed cancer cells. Results There was no significant difference between the two groups in the number of peritoneal carcinoma before operation. After lavage, the detection rate of peritoneal carcinoma cells in hyperthermic perfusion chemotherapy group was significantly lower than that in saline lavage group. Conclusion Intraperitoneal hyperthermic perfusion chemotherapy is safe and effective in the treatment of advanced gastric cancer.