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肾素-血管紧张素系统(RAS)与肾血管性高血压、某些肾性和肾功能衰竭性高血压、原发性醛固酮增多症(简称原醛症)、恶性高血压、分泌肾素的肿瘤等疾病的关系较明确;但对正常血压及高血压状态的确切作用还很不清楚。近年来,主要由于采用了敏感的微量放射免疫测定法,有关RAS基础化学的新进展(特别是肾素轴阻断剂的发现和应用)和肾素分型研究在对指导临床防治、估计预后上所获的启示,使医学研究者日益重视对RAS和原发性高血压关系的研究。RAS不但是一种控制血
Renin-angiotensin system (RAS) is associated with renovascular hypertension, certain renal and renal failure hypertension, primary aldosteronism (primary aldosteronism), malignant hypertension, renin-secreting Cancer and other diseases more clearly the relationship between; but the exact role of normal blood pressure and high blood pressure status is still not clear. In recent years, mainly due to the use of sensitive micro-radioimmunoassay, the new progress of RAS basic chemistry (especially the discovery and application of renin-axis blockers) and renin profiling in guiding the clinical prevention and treatment, prognosis Inspired, medical researchers have increasingly focused on the relationship between RAS and essential hypertension. RAS is not only a kind of control of blood