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目的探讨快速C-反应蛋白(CRP)在儿童急性呼吸道感染疾病中的应用价值。方法对我院2009年10月-12月期间儿科门、急诊上呼吸道感染儿童450例CRP水平进行分析。结果急性呼吸道感染患儿450例中细菌感染组CRP和WBC均明显高于病毒感染组和正常对照组,t检验差异均有统计学意义(P<0.05)。病毒感染组与正常对照组比较差异无统计学意义(P>0.05)。290例CRP阳性患儿经抗生素治疗后明显下降,与治疗前差异有统计学意义(P<0.05),WBC则轻度下降,与治疗前差异无统计学意义(P>0.05)。结论 CRP能初步鉴别细菌感染与病毒感染,可指导临床合理使用抗生素及疗效观察。
Objective To investigate the value of rapid C-reactive protein (CRP) in children with acute respiratory infections. Methods 450 children with pediatric and emergency upper respiratory tract infection in our hospital from October to December 2009 were analyzed for CRP levels. Results The CRP and WBC in 450 cases of children with acute respiratory infection were significantly higher than those of the virus-infected group and the normal control group (P <0.05). There was no significant difference between the virus infection group and the normal control group (P> 0.05). 290 cases of CRP positive children after antibiotic treatment decreased significantly, with the difference between before treatment was statistically significant (P <0.05), WBC decreased slightly, with no significant difference between before and after treatment (P> 0.05). Conclusion CRP can initially identify bacterial infections and viral infections, and can guide clinical rational use of antibiotics and observation of curative effect.